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The product is unique because the omega oils act as a vehicle to enhance the delivery of all other ingredients. Water based compounds cannot penetrate the skin barrier for cellular delivery, but the omega oils do because they are lipophilic.
In vitro studies in Wales have demonstrated enhanced transcutaneous absorption of ibuprofen in the presence of a fatty acid such as omega 3. The latter acts as a "carrier protein" to cross a pigskin barrier Int J Pharm.2003 Aug 11:261(102) 165-9.
In short, MED 0-3's patent-protected compound, comprising omega fatty acids, is a topical analgesic that not only delivers inflammation-fighting omega fatty acids trans-dermally to the source of the pain, but also utilizes omega fatty acids to increase absorption and absorption speed. Further, per Cardiff University's findings, increased concentrations of both methyl salicylate and omega-3 fatty acids are correlated with greater absorption concentration of both inflammation and pain-fighting ingredients in the tissues. It is believed this result would work the same in MED 0-3, increasing pain and inflammation-fighting effectiveness as concentrations of omega fatty acids and NSAIDs are increased in the compound.
Also, recent studies from Harvard (Dr. Serhan's group) have demonstrated a synergism between omega-3 fatty acids and aspirin. They form a very potent newly identified antiinflammatory compound, resolvin-1. This, of course, is MED 0-3's formula.
EFFECTS OF OMEGA-3 FATTY ACIDS | CONSEQUENCE |
Decreased monocyte production of IL-1, IL-2, TNF | Immune system down-regulation |
Decreased endothelial permeability | Anti-inflammation |
Increase in endothelial-dependent vasodilatation | Ana-aggregation |
Eicosanoid-independent inhibition of platelet function | Vasodilation |
Decreased endothelial PDGF | Anti-adhesion |
Chronic pain syndromes and fibromyalgia
Osteoarthritis
Tendonitis/bursitis
Some inflammatory arthropathies
Physical therapy, with phoresis and massage
Muscle cramps
*The topical use of this compound avoids the gastrointestinal and other side effects of commonly used anti-inflammatory oral agents.
** MED 0-3 Bio Cream is also safe for animal use.